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蔡玉真 醫師 Yu-Chen Tsai

放射腫瘤科
參與醫療團隊: 乳癌團隊, 肺癌及食道癌團隊, 頭頸癌及鼻咽癌團隊

專長：

  • 腫瘤放射治療
  • 頭頸腫瘤
  • 肺癌及食道腫瘤
  • 乳房腫瘤

學歷：

  • 台灣大學醫學院 醫學系 學士 1983.09至1990.06

現職：

  • 和信治癌中心醫院 放射腫瘤科 資深主治醫師 2002.07~迄今

經歷：

  • 美國杜克大學醫學中心 放射腫瘤部 兼任助理教授 2001.07~迄今
  • 和信治癌中心醫院放射腫瘤科主治醫師1996.07~2002.06
  • 美國杜克大學放射腫瘤部資深住院醫師1995.07~1996.06
  • 和信治癌中心醫院放射腫瘤科住院醫師1992.07~1995.06
  • 臺大醫院內科住院醫師1990.07~1992.06

專業學會：

  • 台北市醫師公會會員
  • 中華民國放射線醫學會會員
  • 中華民國放射腫瘤學會會員
  • 台灣乳房醫學會會員
  • 國家衛生研究院癌症研究組肺癌研究委員會委員
  • 中華民國兒童癌症基金會顧問醫師

著作：

期刊論文

  1. Cheng SH. Chen CM, Jian JM, Tsai SYC, Liu TW, Liu MC, Chen MC, Lin HH.     Breast-Conserving Surgery and Radiotherapy for Early Breast Cancer. J Formos Med Assoc 95:372-7,1996 (SCI)
  2. Cheng SH, Jian JM, Chan KY, Yu B, Tsai SYC, Liu MC, Chen CM, The Benefit and Risk of Post-Mastectomy Radiation Therapy in High Risk Breast Cancer Patient. Am J Clin Oncol 21(1): 12-17, 1998? (SCI)
  3. Cheng SH, Liu TW, Jian JM, Tsai SYC, Hao SP, Huang CH, Liu MC, Ben Yu, Huang AT. Concomitant Chemotherapy and Radiotherapy for Locally Advanced Nasopharyngeal Carcinoma.  Cancer J Sci Am 3(2): 100-106; 1997. (SCI)
  4. Jian JM, Cheng SH, Tsai SYC, T’so CY, Huang AT, Prosnitz LR. T Classification stage and Clivus Margin as Risk Factors for Determining Locoregional Control by Radiation of Nasopharyngeal Carcinoma. Cancer 82(2): 261-267; 1997 (SCI)
  5. Cheng JC, Cheng SH, Tsai SYC, Jian JM, Huang AT. Concurrent Radiotherapy and Chemotherapy for Tonsillar Carcinoma: Preliminary Report. Chin J Radiol 22: 193-197; 1997. (SCI)
  6. Ch’ang HJ, Jian JM, Cheng SH, Liu MC, Leu SY, Wang FM, Tsai SYC, Tsao MH, Lin HH, Huang AT. Sung JL.  Preoperative Concurrent Chemotherapy and Radiotherapy in Rectal Cancer Patients J Formos Med Assoc. 97(1): 32-37, 1998. 
  7. Cheng SH, Jian JM, Tsai SYC, Chan KY, Yen LK, Chu NM, Tan TD, Tsou MH, Huang AT.  Prognostic Features and Treatment Outcome in Locoregionally Advanced Nasopharyngeal Carcinoma Following Concurrent Chemotherapy and Radiotherapy. Int J Radiation Oncol Biol Phys; Vol.41 No. 4 P.755-762 1998 (SCI)
  8. You DL, Kwan YC, Soong TC, Lin CK, Yen KL, Tsai SYC, Cheng SH, Jian JJ. A comparison of bone spect and MRI in detection of skull base involvement in patients with nasopharyngeal carcinoma. The journal of Nuclear Medicine, 1996. Proceedings of the 46th Annual Meeting.
  9. Cheng SH, Tsai SYC, Yen KL, Jian JJ, Chu NM, Chan KY, Huang AT.  Concomitant Radiotherapy and Chemotherapy for Early-Stage Nasopharyngeal Carcinoma Journal of Clinical Oncology; Vol 18, No 10 (May), 2000, pp 2040-2045 (SCI)
  10. Cheng SH, Jian JJ, Tsai SYC, Yen KL, Chu NM, Chan KY, Huang  Long-Term Survival of Nasopharyngeal Carcinoma Following Concomitant Radiotherapy and Chemotherapy  Int J Radiation Oncol Biol Phys; Vol.48 No.5  P. 1323-1330, 2000 (SCI)
  11. Cheng SH, Yen KL, Jian JJ, Tsai SYC, Chu NM, Chan KY, Huang AT. Examining prognostic factors and patterns of failure in nasopharyngeal carcinoma following concomitant radiotherapy and chemotherapy: impact on future clinical trials  Int J Radiation Oncol Biol Phys; Vol.50 No. 3 P. 717-726, 2001 (SCI)
  12. Jian JJ, Cheng SH, Tsai SYC, Yen KL, Chu NM, Chan KY, Huang AT  Improvement of Local Control of T3 and T4 Nasopharyngeal Carcinoma by Hyperfractionated Radiotherapy and Concomitant Chemotherapy Int J Radiation Oncol Biol Phys; 2002 May (SCI)
  13. Cheng JC, Chen CM, Liu MC, Tsou MH, Jian JM, Cheng SH, Tsai SYC, Huang AT  Locoregional failure of  postmastectomy patients with 1-3 positive axillary lymph nodes without adjuvant radiotherapy   Int J Radiation Oncol Biol Phys; Vol 52 No.4 p.980-988, 2002 (SCI)
  14. Cheng JC, Wu JK, Huang CM, Liu HS, Huang DY, Cheng SH, Tsai SYC, Jian JM, Lin YM, Cheng TI, Horng CF, Huang AT  Radiation-induced liver disease after three-dimensional conformal radiotherapy for patients with hepatocellular carcinoma: dosimetric analysis and implication  Int J Radiation Oncol Biol Phys; Vol 54 No.1 p156-162, 2002  (SCI)
  15. Cheng JC, Wu JK, Huang CM, Liu HS, Huang DY, Tsai SYC, Cheng SH, Jian JM, Huang AT Dosimetric analysis and comparison of three-dimensional conformal radiotherapy and intensity-modulated radiation therapy for patients with hepatocellular carcinoma and radiation-induced liver disease Int J Radiation Oncol Biol Phys; Vol 56 No.1 p229-234, 2003  (SCI)
  16. Huang CM, Cheng JC, Tsai SYC, Liu MC, Chung YL, Cheng SH, Fang WT, Yang PS, Jian JM, Huang AT  Rarely reported liver toxicity in patients who were hepatitis B carrier and underwent chemoirradiation for gastric cancer  Therapeutic Radiology and Oncology vol. 9 no.1 p31-39, march  2002
  17. Chen YH, Cheng JC, Tsai SYC, Cheng SH, Chang DS, Yang LY, Jian JM   Definitive radiotherapy for the patients with prostatic adenocarcinoma: Analysis of short-term outcome and prognostic factors  Therapeutic Radiology and Oncology vol. 10 no.1 p1-9 2003
  18. Cheng JC, Liu MC, Tsai SYC, Fang WT, Jian JM, Sung JL Unexpectedly Frequent Hepatitis B Reactivation by Chemoradiation in Postmastectomy Patients Cancer Nov 1, 2004, vol 101 p 2126-2133 
  19. Feng AC, Wu MC, Tsai SY, et al. Prevertebral muscle involvement in nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. Jul 15 2006; 65(4):1026-1035.
  20. Cheng SH, Tsai SY, Yen KL, et al. Prognostic significance of parapharyngeal space venous plexus and marrow involvement: potential landmarks of dissemination for stage I-III nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. Feb 1 2005; 61(2):456-465.
  21. Yih-Lin Chung, James Jer-Min Jian, Skye Hongiun Cheng, Stella Y.C. Tsai, Vincent P. Chuang, Thomas Soong, Yu-Mong Lin, and Cheng-Fang Horng  Sublethal Irradiation Induces Vascular Endothelial Growth Factor and Promotes Growth of Hepatoma Cells: Implications for Radiotherapy of Hepatocellular Carcinoma Clin Cancer Res 2006 12: 2706-2715
  22. Brain Stem Doses for Patients of T3/T4 Nasopharyngeal Carcinoma Treated by Bid Irradiation and Concomitant Chemotherapy  局部嚴重性鼻咽癌病人一天兩次放射治療合併化學治療之腦幹劑量分佈長期追蹤研究成果 蔡玉真(Stella Y. C. Tsai);鄭鴻鈞(Skye Hongiun Cheng);簡哲民(James Jer-Min Jian);黃昭明(Chao-Ming Huang);閻愷正(K. Lawrence Yen);詹光裕(Kwan-Yee Chan);呂思韻(Szu-Yun Leu);林燕君(Yen-Chun Lin);褚乃銘(Nei-Min Chu);譚傳德(Tran-Der Tan);謝政毅(Cheng-Yee Hsieh);曾美華(Mei-Hua Tsou);林敬原(Ching-Yuan Lin);黃達夫(Andrew T. Huang)  放射治療與腫瘤學  12卷3期 (2005/09) 167-180
  23. Cheng SH, M.D., Stella Y.C. Tsai, M.D., A prognostic scoring system for locoregional control in nasopharyngeal carcinoma following conformal radiotherapy Int. J. Radiation Oncology Biol. Phys., Vol. 66, No. 4, pp. 992–1003, 2006

研討會論文

  1. Stella YC Tsai, Cheng SH, Jian JM, Chan KY, Tsai, MJ.  Significant Prognosticators after Primary Radiotherapy in 67 Patients Nondisseminated Nasopharyngeal Carcinoma Evaluated by Magnetic Resonance Image. 2nd Congress of Asian and Oceanian Society of Neuro radiology and Head and Neck Radiology Mar 23- 27 1997.
  2. Stella Y.C. Tsai, Cheng SH, Jian JM, Yen KL, Chan KY, Leu SY, Lin YC The Significance of Prevertebral Muscle Involvement of Nasopharyngeal Carcinoma Investigated by MR Imaging  2000第五屆台灣癌症聯合學術年會
  3. Jian JM, Cheng SH, Stella Y.C. Tsai, Yen KL, Chan KY, Leu SY, Lin YC Improvement of local Control of T3 and T4 Nasopharyngeal Carcinoma By BID Radiation and Chemotherapy     2000第五屆台灣癌症聯合學術年會
  4. Cheng SH, Jian JM, Stella Y.C. Tsai, Yen KL, Chan KY, Leu SY, Lin YC Long Term Survival of Nasopharyngeal Carcinoma Following Concomitant Radiotherapy And Chemotherapy   2000第五屆台灣癌症聯合學術年會
  5. Stella Y.C. Tsai, SH Cheng, KY Chan, .JM Jian, Lawrence Yen, Szu-Yun Leu. Yen-Chun Lin. Nei-Min Chu, Andrew T. Huang,  Clinical Significance of Pre-Vertebral Muscle Infiltration in Nasopharyngeal Carcinoma   2001 Annual meeting of ASTRO (American Society for Therapeutic Radiology and Oncology)
  6. Stella Y.C. Tsai, SH Cheng, JM Jian, K. Lawrence Yen, Nei-Min Chu, Kwan-Yee Chan, Tran-Der Tan, Ching-Yuan Lin, Chao-Ming Huang, Yen-Chun Lin, Cheng-Yee. Hsieh, Andrew T. Huang,   Brain Stem Doses for Patients of T3/T4 Nasopharyngeal Carcinoma Treated By BID Irradiation and Concomitant Chemotherapy  UICC NPC WORKSHOP 2003 HONGKONG
  7. Chia-Chuan Liu, Stella Y.C. Tsai, Wei-Tse Fang, Current Treatment Strategy for Thoracic Esophageal Cancer in SYSCC and preliminary report of surgical result 2004台灣外科醫學會
  8. Stella Y.C. Tsai ; Dong-Ling You ; JM Jian, , Skye Cheng, ; Yih-Lin Chung; Hsin-Hsuan Chen, Lawrence Yen, Ching-Yuan Lin, Shyuang-Der Terng, Mei-Hua Tsou, ; Kwan-Yee Chan, Andrew Huang,  Value of Positron Emission Tomography with [F-18] Fluorodeoxyglucose in Patients with T4 or N3, M0 Nasopharyngeal Cancer: A Prospective Study   2004 Annual meeting of ASTRO (American Society for Therapeutic Radiology and Oncology)
  9. Stella Y.C. Tsai; CM Chen, MC Liu, JJ Jian, Skye Cheng, MH Tsou, MC Lu, Andrew T. Huang  Predictors of Local-Regional Recurrence After Neoadjuvant Chemotherapy and Mastectomy With Radiation  2004 中華民國放射線醫學五十三次學術研討會
  10. Stella Y. C. Tsai, Tsung-Yen Cheng, Mei-Ching Liu, Skye H. Cheng, Postoperative adjuvant chemo radiation in completely resected locally advanced gastric cancer: Taiwan Experience 2006 Gastrointestinal Cancers Symposium ASCO ASTRO SSO
  11. Stella Y.C. Tsai, JM Jian, Skye Cheng, Intensity-Modulated Radiation Treatment for Nasopharyngeal Carcinoma-The Koo Foundation Sun Yet-Sen. Cancer Center (KFSYSCC) Experience  2008 Annual meeting of ASTRO (American Society for Therapeutic Radiology and Oncology)
  12. Stella Y. C. Tsai, Skye Cheng, JM Jian, Andrew T. Huang Long-Term Results of Hyperfractionated Radiation Therapy and Concomitant Chemotherapy for T4 and T4 Nasopharyngeal Carcinoma The 15th Taiwan Joint Cancer Conference,2010

Research Experience:

  1. Cheng SH, Tsai SYC, Jian JM, Yen LK, Huang AT. A Comprehensive Data Base and A New Staging System for NPC (Grant No. NHRI-GT-EX89P930L) (1999/7/1-2002/6/30)
  2. Cheng SH, Jian JM, Tsai SYC. Methods for determining safe margins of radiation to the Clinical Target Volume and Gross Tumor Volume in the treatment of NPC. (NSC 89-2320-B-368 -002 -M08) (1999/08/01 - 2000/07/31)

Major Research Interests:

  1. Prognostic factors detected by MRI image for nasopharyngeal patients.
  2. Brain stem, spinal cord and optic nerve radiation tolerance dose for hyperfractionation radiation treatment.
  3. Concurrent chemoirradiation for nasopharyngeal cancer. New chemotherapy regimen to decrease distant metastasis.

Presentations:

  1. 3D conformal therapy experience at SYSCC. 3D Conformal Therapy Symposium 1997 at KF-SYSCC, Taipei, Taiwan
  2. Clinical Application of Interstitial Brachytherapy. The 2nd International Radiological QA Conference workshop in Taiwan: Brachytherapy QA and Clinical experience April 1998, Taipei, Taiwan
  3. Radiotherapy for prostate cancer. Prostrate Cancer Symposium 1997 at KF-SYSCC, Taipei, Taiwan
  4. Brain stem dose to hyperfractionated Radiotherapy of T3 and T4 Nasopharyngeal  Cancer   New development in Radiation Oncology.   Sun Yat-Sen Cancer Center and The Chinese Society for Therapeutic Radiology and Oncology, Taipei, R.O.C. April 22, 2000
  5. Brain Stem Dose Data for T3 and T4 NPC by BID Radiation and Chemotherapy. New Frontier of Radiation Oncology June 3, 2000. VGH, Taipei
  6. The benefit and side effect of postmastectomy radiation therapy for breast cancer. The Chinese Society for Therapeutic Radiology and Oncology, Taipei, R.O.C. January 6, 2001
  7. Radiotherapy for Gastric cancer. The Chinese Society for Therapeutic Radiology and Oncology, Taipei, R.O.C. January 19, 2002
  8. KFSYSCC Nasopharyngeal Cancer Surveillance Guidelines. The Chinese Society for Therapeutic Radiology and Oncology, Taipei, R.O.C. 2005
  9. 2008 ASCO head and neck cancer; esophageal cancer The Chinese Oncology Society July 5, 2008
  10. 2008 ASCO head and neck cancer; esophageal cancer The Chinese Society for Therapeutic Radiology and Oncology, Taipei, R.O.C. Aug 2, 2008
  11. 2008 ASCO and ASTRO the Chinese Society for Therapeutic Radiology and Oncology, Taipei, R.O.C. April 25, 2009
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