Tsung-Yen Cheng M.D.

Medical Team: Breast Cancer, Hepatobiliary & Upper Gastrointestinal Cancer, Endocrine Tumor

Current Title

  • Chief, Department of Surgery, 2011-present
  • Senior Member, Department of Surgery, 2011-present

Languages Spoken

  • Mandarin Chinese
  • English

Education and Training

1984-1991 Taipei Medical College, Taiwan, MD, Medicine
1993-1997 Residency, Surgery, Taipei Veterans General Hospital, Taiwan
1997-1998 Chief Resident, Surgery, Taipei Veterans General Hospital, Taiwan
2002-2003 Fellowship, Surgical Oncology, Duke University Medical Center, Durham, NC, USA

Professional Experience

1998-2011 Attending Physician, General Surgery, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan 
2011-present Senior Member, Surgery, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan 
2011-present Chief, Surgery, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan

Selected Publications

  1. Cheng TY, Su CH, Shyr YM, Lui WY. Management of pancreatic lesions in von Hippel-Lindau disease. World J Surg 1997; 21:307-312.
  2. Abdel-Wahab Z, Kalady MF, Emani S, Onaitis MW, Abdel-Wahab OI, Cisco R, Wheless L, Cheng TY, Tyler DS, Pruitt SK. Induction of anti-melanoma CTL response using DC transfected with mutated mRNA encoding full-length Melan-A/MART-1 antigen with an A27L amino acid substitution. Cell Immunol 2003; 224:86-97.
  3. Cheng TY, Grubbs E, Abdul-Wahab O, Leu SY, Hung CF, Petros W, Aloia T, Fedrau R, Pruitt S, Colvin M, Friedman H, Tyler D. Marked variability of melphalan plasma drug levels during regional hyperthermic isolated limb perfusion. Am J Surg 2003; 186:460-467.
  4. Grubbs EG, Abdel-Wahab O, Cheng TY, Abdel-Wahab Z, Peterson B, Pruitt SK, Colvin OM, Friedman HS, Tyler DS. In-transit melanoma: The role of alkylating-agent resistance in regional therapy. J Am Coll Surg 2004; 199:419-427.
  5. Grubbs EG, Ueno T, Abdel-Wahab O, Cheng TY, Pruitt SK, Michael Colvin O, Friedman HS, Tyler DS. Modulation of resistance to regional chemotherapy in the extremity melanoma model. Surgery 2004; 136:210-218.
  6. Huang Y, Tsung JS, Lin CW, Cheng TY. Intrahepatic cholangiocarcinoma with lymphoepithelioma-like carcinoma component. Ann Clin Lab Sci 2004; 34:476-480.
  7. Abdel-Wahab OI, Grubbs E, Viglianti BL, Cheng TY, Ueno T, Ko S, Rabbani Z, Curtis S, Pruitt SK, Dewhirst MW, Tyler DS. The role of hyperthermia in regional alkylating agent chemotherapy. Clin Cancer Res 2004; 10:5919-5929.
  8. Aloia TA, Grubbs E, Onaitis M, Mosca PJ, Cheng TY, Seigler H, Tyler DS. Predictors of outcome after hyperthermic isolated limb perfusion: role of tumor response. Arch Surg 2005; 140:1115-1120.
  9. Shih NN, Tsung JS, Yang AH, Tsou MH, Cheng TY. A unique pancreatic tumor with exclusive hepatocytic differentiation. Ann Clin Lab Sci 2006; 36:216-221.
  10. Ueno T, Ko SH, Grubbs E, Yoshimoto Y, Augustine C, Abdel-Wahab Z, Cheng TY, Abdel-Wahab OI, Pruitt SK, Friedman HS, Tyler DS. Modulation of chemotherapy resistance in regional therapy: a novel therapeutic approach to advanced extremity melanoma using intra-arterial temozolomide in combination with systemic O6-benzylguanine. Mol Cancer Ther 2006; 5:732-738.
  11. Cheng TY, Sheth K, White RR, Ueno T, Hung CF, Clary BM, Pappas TN, Tyler DS. Effect of neoadjuvant chemoradiation on operative mortality and morbidity for pancreaticoduodenectomy. Ann Surg Oncol 2006; 13:66-74.
  12. Beasley GM, Petersen RP, Yoo J, McMahon N, Aloia T, Petros W, Sanders G, Cheng TY, Pruitt SK, Seigler H, Tyler DS.  Isolated limb infusion for in-transit malignant melanoma of the extremity: a well-tolerated but less effective alternative to hyperthermic isolated limb perfusion. Ann Surg Oncol 2008; 15:2195-2205.
  13. McMahon N, Cheng TY, Beasley GM, Spasojevic I, Petros W, Augustine CK, Zipfel P, Padussis JC, Sanders G, Tyler DS.  Optimizing melphalan pharmacokinetics in regional melanoma therapy: does correcting for ideal body weight alter regional response or toxicity? Ann Surg Oncol 2009; 16:953-961.
  14. Cheng TY, Chen CM, Lee MY, Lin KJ, Hung CF, Yang PS, Yu BL, Yang CE, Tsai  TJ, Lin CW.  Risk Factors Associated with Conversion from Nonmalignant to Malignant Diagnosis After Surgical Excision of Breast Papillary Lesions. Ann Surg Oncol 2009, 16:3375-3379.
  15. Shih-Hsuan Wu, Ben-Long Yu, Chii-Ming Chen, Chen-En Yang, Tzu-Jung Tsai, Chung-Wei Lin, Tsung-Yen Cheng, Dong-Ling You, Yu-Yi Huang, Pei-Ing Lee, Mei-Hua Tsou, Ming-Yuan Lee, Ai-Ying Chuang, Wen-Hui Ku, Christopher K.J. Lin, Woan-Chwen Jaw, Wan-Chen Tsai, Po-Sheng Yang.  Experience with Sentinel Lymph Node Biopsy in Early Breast Cancer Patients at a Cancer Center. J. Cancer Res. Pract. 26(1), 21-27, 2010.
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