Ming-Yuan Lee M.D.

Pathology and Laboratory Medicine
Medical Team: Thoracic Oncology, Lymphoma & Leukemia, Soft Tissue Sarcoma & Melanoma

Current Title

  • Deputy Director, Department of Pathology, 2012-present

Specialties

  • Pathology of Lung and Hematological Diseases

Clinical Interests

  • Clinicopathological study of malignant lymphomas and leukemias in Taiwan
  • Histopathologic correlation of hepatocellular carcinoma after transcatheter arterial chemoembolization with polyvinyl alcohol particle of various sizes
  • Prognostic implications of histological patterns and tumor necrosis for stage I lung adenocarcinoma
  • The association of Rab5A protein with axillary lymph node metastasis in breast cancer patients
  • Risk factors associated with conversion from nonmalignant to malignant diagnosis after surgical excision of breast papillary lesions

Languages Spoken

  • Mandarin Chinese
  • Taiwanese
  • English

Education and Training

1981-1985 National Taiwan University, Taiwan, BD
1985-1990 National Yang-Ming University, Taiwan, MD, Medicine
1990-1992 Residency, Internal Medicine, Hua-Lien Veterans Hospital, Taiwan 
1992-1995 Graduate Studies, Experimental Pathology, Duke University, Durham, NC, USA
1997-2001 Residency, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan
2001-2002 Fellowship, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan

Professional Experience

2001-2008 Attending Physician (Assistant Member), Anatomic Pathology, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan
2008-present Attending Physician (Associate Member), Anatomic Pathology, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan
2008-present Lecturer, Pathologic Diseases, National Yang-Ming University, Taiwan 
2012-present Deputy Director, Pathology, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan

Professional Memberships

  • Member, Taiwan Society of Pathology
  • Member, International Academy of Pathology, Taiwan Division
  • Member, Taiwan Society of Clinical Cytology
  • Member, Taiwan Society of Medicine

Selected Publications

  1. Ming-Yuan Lee, Vincent P Chuang, Chao-Jung Wei, Tsung-Yen Cheng, Ming-Chih Cheng. Histopathologic correlation of hepatocellular carcinoma after transcatheter arterial chemoembolization with polyvinyl alcohol particle of various sizes. Euro J Radiol 2012 Sep 81;1976-1979. (SCI)
  2. Chung-Jen Huang, An-Chen Feng, Yueh-Fu Fang, Wen-Hui Ku, Nei-Min Chu, Chih-Ten Yu, Chia-Chuan Liu, Ming-Yuan Lee, Li-Han Hsu, Stella Y.C. Tsai, Chih-Shiun Shih. Multimodality treatment and long-term follow-up of the primary lymphoepithelioma-like carcinoma. Clin Lung Cancer 2012 Sep 13;359-362.
  3. Chung-Jen Huang, An-Chen Feng, Yueh-Fu Fang, Wen-Hui Ku, Nei-Min Chu, Chih-Ten Yu, Chia-Chuan Liu, Ming-Yuan Lee, Li-Han Hsu, Stella Y.C. Tsai, Chih-Shiun Shih. Multimodality treatment and long-term follow-up of the primary lymphoepithelioma-like carcinoma. Clin Lung Cancer 2012 Sep 13;359-362
  4. Po-Sheng Yang, Pen-Hui Yin, Ling-Ming Tseng, Chin-Hua Yang, Chih-Yi Hsu, Ming-Yuan Lee, Chen-Fang Hung, Ching-Wen Chi. Rab5A is associated with axillary lymph node metastasis in breast cancer patients. Cancer Science 2011 Oct (SCI)
  5. Yu-Yi Huang, Dong-Ling You, Mei-Ching Liu, Tran-der Tan, Pei-Ing Lee, Ming-Yuan Lee. Underperformance of Gallium-67 scan is greater in relapse than in initial staging, compared with FDG PET. Clin Nuclear Med 2011;36:867-871(SCI)
  6. Po-Sheng Yang, Chii-Ming Chen, Mei-Chin Liu, Jer-Ming Jiang, Chen-Fang Hung, Ben-Long Yu, Ming-Yuan Lee. Radiotherapy can decrease locoregional recurrence and increase survival in mastectomy patients with T1 to T2 breast cancer and one to three positive nodes with negative estrogen receptor and positive lymphovascular invasion. International Journal of Radiation Oncology, Biology, Physics. 2010;77:516-522. (SCI)
  7. Tsung-Yen Cheng, Chii-Ming Chen, Ming-Yuan Lee, Kwang-Jane Lin, Cheng-Fung Hung, Po-Sheng Yang et al. Risk factors associated with conversion from nonmalignant to malignant diagnosis after surgical excision of breast papillary lesions. Ann Surg Oncol 2009;16:3375-3379.(SCI)
  8. Yih-Lin Chung, Ming-Yuan Lee and Newman N.M. Pui. Epigenetic therapy using the histone deacetylase inhibitor for increasing therapeutic gain in oral cancer: prevention of radiation-induced oral mucositis and inhibition of chemical-induced oral carcinogenesis. Carcinogenesis. 2009;30:1387-1397.(SCI)
  9. Mei-Hua Tsou, Shu-Fen Tsai, Kwan-Yi Chan, Cheng-Fang Horng, Ming-Yuan Lee, Ai-Ying Chuang and Ming-Chih Chern. CT-guided needle biopsy: value of on-site cytopathologic evaluation of core specimen touch preparations. J Vasc Interv Radiol. 2009;20:71-76.(SCI)
  10. Yih-Lin Chung, Ming-Yuan Lee, Cheng-Fang Horng, James Jer-Ming Jiang, Skye Hongiun Cheng, Stella Y. Tsai, Cheng-I Hsieh, Lawrence K. Yen and Ching-Yuan Lin. Use of combined molecular makers for prediction of clinical outcomes in locally advanced tonsillar cancers treated with chemoradiotherapy alone. Head and Neck. 2009;31:8-20.(SCI)
  11. Ming-Yuan Lee, Vincent P. Chung, C-Y. Cheng, P-S Yang, Ming-Tsu Chern and Zoe Lin. The effect of polyvinyl alcohol particle size in the chemoembolization for hepatocellular carcinoma followed by tumor resection: correlation with histopathological features. Histopathology. 2008;53(suppl. 1):260.(abs) (SCI)
  12. Ming-Yuan Lee, Tran-Der Tan and An-Chen Fen. Clinicopathological analysis of acute myeloid leukemia in a single institution: Biphenotypic acute myeloid leukemia may not be an aggressive subtype. Journal of the Chinese Medical Association 2007;70:269-273. (SCI)
  13. Tran-Der Tan, Ming-Yuan Lee. The shift of treatment for nasal and nasal-type NK/T cell lymphoma, ten years experience and prognostification analysis in a single institution. Haematologica 2007; 92(suppl.1): 263. (abs) (SCI)
  14. Chung-Jen Huang, Kwen-Yee Chan, Ming-Yuan Lee, Li-Han Hsu, Nei-Min Chu, AN-Chen Feng, Chih-Teng Yu and Horng-Chyuan Lin. Computed tomography characteristics of primary pulmonary lymphoepithelioma-like carcinoma. British Journal of Radiology 2007;80:803-806.(SCI)
  15. Ming-Yuan Lee, Tsung-Yen Cheng, Wei-Tse Fang and An-Chen Feng. Clinicopathological analysis of gastrointestinal stromal tumor: nine-year experience in a single institution. Modern Pathology 2006;19(3):63. (abs)(SCI)
  16. Ming-Yuan Lee, Tran-Der Tan, An-Chen Feng and Mei-Ching Liu. Clinicopathological analysis of 598 malignant lymphomas in Taiwan: Seven-year Experience in a single institution. American Journal of Haematology 2006;81:568-575. (SCI)
  17. Ming-Yuan Lee, Tran-Der Tan and An-Chen Feng. Clinicopathological study of Hodgkin lymphoma in a cancer center in Taiwan. Clinical and Laboratory Hematology 2005;27:379-383. (SCI)
  18. Ming-Yuan Lee, Tran-Der Tan, An-Chen Feng and Mei-Ching Liu. Clinicopathological analysis of malignant lymphoma in Taiwan according to WHO Classification: Low incidence of T/NK Cell lymphoma and Hodgkin lymphoma. Haematologica/The Hematology Journal 2005;90:1703-1705. (SCI)
  19. Ming-Yuan Lee, Mei-Hua Tsou, Tran-Der Tan and Mei-Chun Liu. Clinicopathological analysis of T cell lymphoma in Taiwan according to WHO classification: high incidence of enteropathy-typed intestinal T cell lymphoma. European Journal of Haematology 2005;75:221-226. (SCI)
  20. Yih-Lin Chung, Ming-Yuan Lee, Ae-June Wang and Lin-Fen Yao. A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of Rheumatoid arthritis. Molecular Therapy 2003;8:707-717. (SCI)
  21. Ming-Yuan Lee, Mei-Hua Tsou, Yahn-Kun Chiou, Daniel S. Cheng and Jeffrey S-H Tsung. Benign ovarian mucinous cystadenoma with extremely high serum level of tumor marker CA19-9: a case report. J Biomedical and Laboratory Science 2001;13:95-98. (non-SCI)
  22. Ming-Yuan Lee, Mei-Hua Tsou, Mary H. Cheng, Daniel S. Chang, Alex Lien-Yen and Jen-Sheng Ko. Clinical application of NMP22 and urine cytology in patients with hematuria or history of urothelial carcinoma. World Journal of Urology 2000;18:401-405. (SCI)
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