Li-Han Hsu M.D.

General Internal Medicine
Medical Team: Thoracic Oncology, Intensive Care

Current Title

  • Attending Physician, Division of Pulmonary and Critical Care Medicine, 1996-present 

Specialties

  • Pulmonary and critical care medicine

Clinical Interests

  • Interventional pulmonology
  • Respiratory care
  • Pleural diseases
  • Lung cancer epidemiology and molecular biology
  • Lung cancer screening

Languages Spoken

  • Taiwanese
  • Japanese
  • English
  • Mandarin Chinese

Education and Training

1982-1989 Taipei Medical College, Taiwan, MD, Medicine
1988-1989 Internship, National Taiwan University Hospital, Taiwan
1989-1991 Military Physician, Navy, Taiwan
1991-1994 Residency, Section of Respiratory Therapy, Taipei Veterans General Hospital, Taiwan
1994-1996 Chief Resident, Section of Respiratory Therapy, Taipei Veterans General Hospital, Taiwan

Professional Experience

1996-present Attending Physician, Pulmonary and Critical Care Medicine, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan
1998-present Adjunct Attending Physician, Section of Respiratory Therapy, Taipei Veterans General Hospital, Taiwan
2010-present Clinical Associate Professor, National Yang-Ming University, Taiwan

Professional Memberships

  • Board of the Society of Internal Medicine, Taiwan, 1994
  • Board of the Society of Emergency and Critical Care Medicine, Taiwan, 1996
  • Board of the Society of Pulmonary and Critical Care Medicine, Taiwan, 1996
  • Member, International Association for the Study of Lung Cancer (IASLC), 2000-present
  • Member, World Association for Bronchology (WAB), 2000

Selected Publications

  1. Hsu LH, Wang JH*. Treatment of carbon monoxide poisoning with hyperbaric oxygen. Chin Med J (Taipei) 1996; 58:407-13
  2. Hsu LH*, Lien TC, Wang JH. Chylothorax: a complication of internal jugular vein catheterization. Chin Med J (Taipei) 1997; 60:57-61
  3. Hsu LH*, Wang JH. Management of dyspnea in patients with cancer. Thorac Med (Taiwan) 1997; 12:197-201
  4. Hsu LH*, Mao TL, Shih CS, Chou TY, Huang SN. Well differentiated fetal adenocarcinoma of the lung. J Formos Med Assoc 2000; 99:425-7
  5. Hsu LH*, Lin KJ, Chu NM. Lungcancer screening- time to reexamine its role. J Intern Med Taiwan 2000; 11:177-83
  6. Hsu LH*, Chen JC, Tsai GJS, Tsou MH, Hsu WH. Thymic hyperplasia in a patient with Graves' disease. Chin Med J (Taipei) 2001; 64:115-20
  7. Hsu LH*, Liu CC, Lin CY, Yen KL, Chan KY. Self-expandable metallic tracheobronchial stent insertion and endobronchial electrocautery employing flexible bronchoscopy - preliminary results at a cancer center. J Formos Med Assoc 2002; 101:399-405
  8. Hsu LH*, Tsou MH, You DL, Hsu WH. Primary pulmonary paraganglioma. Chin Med J (Taipei) 2002; 65:446-9
  9. Hsu LH*, Lee WC, Lin CM, Jiang JS. Insertion of self-expandable metallic stent (SEMS) in an adult having anomalous right pulmonary artery with right main bronchus compression. J Bronchol 2003, 10:201-3
  10. Hsu LH*, Ko JS, Liu CC. Education and experience improve the performance of transbronchial needle aspiration (TBNA) - a learning curve at a cancer center. Chest 2004; 125:532-40
  11. Hsu LH*, Ko JS, You DL, Chu NM. Transbronchial needle aspiration guided by integrated positron emission tomography and computed tomography - a preliminary report. J Bronchol 2005; 12:76-80
  12. Tsai JP, Chen HW*, Cheng ML, Liu HK, LeeYP, Hsieh CL, Luh KT, Wu CW, Hsu LH, Chao TY, Wang WH, Chang CM, Ting CC. Analysis of host versus tumor interaction in cancer patients: opposing role of transforming growth factor-b1 and interleukin 6 in the development of in situ tumor immunity. Immunobiology 2005; 210:661-71
  13. Hsu LH*, Soong Thomas C, Feng AC, Liu MC. Intrapleural urokinase for the treatment of loculated malignant pleural effusions and trapped lungs in medically inoperable cancer patients. J Thorac Oncol 2006; 1:460-7
  14. Chang GC, Liu KJ, Hsieh CL, Hu TS, Charoenfuprasert S, Liu HK, Luh KT, Hsu LH, Wu CW, Ting CC, Chen CY, Chen KC, Yang TY, Chou TY, Wang WH, Whang-Peng J, Shih NY*. Identification of alpha-enolase as an autoantigen in lung cancer: its overexpression is associated with clinical outcomes. Clin Cancer Res 2006; 12:5746-54
  15. Wang KM, Liu CC*, Shih CS, Hsu LH. Extralobar bronchopulmonary sequestration complicated by Nocardia Asteroides infection: a case report. Thorac Med (Taiwan) 2007; 22:367-72
  16. Hsu LH*, Ko JS, You DL, Liu CC, Chu NM. Transbronchial needle aspiration accurately diagnoses sub-centimetre mediastinal and hilar lymph nodes detected by integrated positron emission tomography and computed tomography. Respirology 2007;12, 848–55
  17. Huang CJ*, Chan KY, Lee MY, Hsu LH, Chu NM, Feng AC, Yu CT, Lin HC. Computed tomography characteristics of primary pulmonary lymphoepithelioma-like carcinoma. Br J Radiol. 2007;80:803-6
  18. Liu CC, Wang KM, Hsu LH*. Tracheobronchial self-expanding metallic stents in patients with central airways obstruction. J Bronchol 2008;15:11-16
  19. Hsu LH, Liu CC, Nobuyama S, Miyazawa T*. Novel use of a disposable curved stent insertion plastic device for silicone stent placement in patients with limited neck extension. J Bronchol Intervent Pulmonol 2009; 16:15-7
  20. Huang CJ*, You DL, Lee PI, Hsu LH, Liu CC, Shih CS, Shih CC, Tseng HC. Characteristics of integrated 18F-FDG PET/CT in pulmonary cryptococcosis. Acta Radiol. 2009;50:374-8
  21. Hsu LH, Chu NM*, Liu CC, Tsai SYC, You DL, Ko JS, Lu MC, Feng AC. Sex-associated differences in non-small cell lung cancer in the new era: Is gender an independent prognostic factor? Lung Cancer 2009; 66:262-7
  22. Huang CJ*, Feng AC, Fang YF, Ku WH, Chu NM, Yu CT, Liu CC, Lee MY, Hsu LH, Tsai SYC, Shih CS, Wang CL. Multimodality Treatment and Long-Term Follow -up of the Primary Pulmonary Lymphoepithelioma-like Carcinoma. Clinical Lung Cancer 2012;13:359-62

(*corresponding author)

Conference Papers:

  1. Hsu LH, Liu CC, Chen C. Expandable metallic stent (UltraflexÒ) in a patient with esophageal carcinoma and tracheal invasion. [Abstract]. Proceedings of Annual Congress of Taiwan Society of Pulmonary and Critical Care Medicine, Taipei Taiwan, 9 -10 December, 2000
  2. Hsu LH, Mao TL, Tsou MH, Ko JS. Transbronchial needle aspiration (TBNA) at a cancer center- a preliminary clinical experience. [Abstract]. Proceedings of Annual Congress of Taiwan Society of Pulmonary and Critical Care Medicine, Taipei, Taiwan, 9 -10 December, 2000
  3. Hsu LH, Liu MC, Soong Thomas C. Use of intrapleural urokinase (IPUK) in the management of multiloculated malignant pleural effusion. [Abstract]. Proceedings of the 26th International Congress of Internal Medicine, Kyoto, Japan, 26 -30 May, 2002
  4. Hsu LH, Liu CC, Lin CY, Yen KL, Chan KY. Self-expandable metallic tracheobronchial stent insertion and endobronchial electrocautery employing flexible bronchoscopy - preliminary results at a cancer center in Taiwan. [Abstract]. Proceedings of the 12th World Congress for Bronchology, Boston, MA USA, 16-19 June, 2002 
  5. Hsu LH, Lee WC, Lin CM, Jiang JS. Insertion of self-expandable metallic stent (SEMS) in a patient having anomalous right pulmonary artery with right main bronchus compression. [Abstract]. Proceedings of the 12th World Congress for Bronchology, Boston, MA USA, 16-19 June, 2002 
  6. Hsu LH, Liu CC, Ko JS. Focused education and experience improve the performance of transbronchial needle aspiration (TBNA) - a learning curve at a cancer center. [Abstract]. Proceedings of the 7th Congress of Asian Pacific Society of Respirology, Taipei, Taiwan, 25 -28 October, 2002
  7. Hsu LH, Soong Thomas C, Feng AC, Liu MC. Intrapleural urokinase in the treatment of loculated malignant pleural effusions. [Abstract]. (submitted as poster and selected for oral presentation) Proceedings of the 13th World Congress for Bronchology, Barcelona, Spain, 20-23 June, 2004
  8. Hsu LH, Ko JS, You DL, Liu CC, Chu NM. Therole of transbronchial needle aspiration in patients with positive hilar-mediastinal lymph nodes on integrated positron emission tomography and computed tomography. [Abstract]. (oral presentation only) Proceedings of the 1st Asian Pacific Congress on Bronchology and Interventional Pulmonology, Chiba, Japan, 26-27 November, 2005
  9. Hsu LH, Liu CC, Wang KM. Tracheobronchial self-expanding metallic stents in cancer patients with complications involving central airways.[Abstract]. Proceedings of the 2nd Asian Pacific Congress on Bronchology and Interventional Pulmonology, Singapore, 12-16 July, 2007
  10. Hsu LH, Chu NM, Liu CC, Tsai Stella YC, You DL, Ko JS, Feng AC, Lu MC. Gender-associated differences in clinico-pathologic characteristicsand survivalfrom non-small cell lung cancerin the new era (submitted as poster and selected for oral presentation) [Abstract]. Proceedings of the 12thWorld Conference on Lung Cancer, Seoul, Korea, 2-6 September, 2007
  11. Hsu LH, Miyazawa T, Liu CC, Lin CY, Terng SD. Novel use of a disposable curved stent insertion plastic device for silicone stenting in post-radiotherapy head and neck cancer patient with rigid fibrotic neck not feasible for rigid bronchoscopy. [Abstract]. Proceedings of the 15th World Congress for Bronchology, Tokyo, Japan, 30 March -2 April, 2008
  12. Hsu LH,Liu KJ, Tsai MF, Wu CR, Hsieh SC, Feng AC, Chu NM, Kao SH. Estrogen Up-regulates Osteopontin Expression and Synergy with Epidermal Growth Factor Promote Lung Cancer Cell Migration. J Thorac Oncol 2011; 6(supplement 2):S1001-2. 14th World Conference on Lung Cancer, Amsterdam, the Netherlands, 3-7 July, 2011 

Journal Reviewer:

  1. Chest
  2. Lung Cancer
  3. Journal of Thoracic Oncology

Awards

  1. 1994 Honors for Distinguished Academic Record in Clinical Medicine, Veterans General Hospital, Taipei, Taiwan
  2. 2002 Young Investigator's Award (YIA), 26th International Congress of Internal Medicine, Kyoto, Japan
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